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ISSN: 1949-0119 (Print)
ISSN: 1949-0127 (Online)
Literature Review Open Access

The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain: A Literature Review

Racha Hajj1 and Camille Haddad1
  • 1 Saint-Joseph University, Lebanon

Abstract

The aim of this article is to describe the new actions of botulinum toxin A for chronic pain treatment. BT/A inhibits the exocytosis of synaptic vesicles containing the pain mediators neurotransmitters, reduces the post traumatic trigeminal neuralgia pain, inhibits the release of microglia derived TNF-α as well as other pro inflammatory cytokines, viable treatment option in the case of patients who do not respond to conservative treatment methods of chronic pain (medication) BT/A is an emerging treatment for chronic pain; patients with severe chronic facial pain, not responding to conventional treatments, can respond to botulinum type a injections

Current Research in Dentistry
Volume 12 No. 1, 2021, 62-70

DOI: https://doi.org/10.3844/crdsp.2021.62.70

Submitted On: 5 June 2021 Published On: 10 August 2021

How to Cite: Hajj, R. & Haddad, C. (2021). The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain: A Literature Review. Current Research in Dentistry, 12(1), 62-70. https://doi.org/10.3844/crdsp.2021.62.70

Open AccessCopyright: © 2021 Racha Hajj and Camille Haddad. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • Anti Inflammatory
  • Anti Nociceptive
  • BiTox/AA
  • Botulinum Toxin A
  • Chronic Pain
  • Derm-BOT