Disseminated Cryptococcal Disease with Skeletal and Pulmonary Involvement
- 1 Department of Internal Medicine, Geisinger Medical Center, United States
- 2 Department of Infectious Diseases, Geisinger Medical Center, United States
- 3 Department of Pharmacy, Geisinger Medical Center, United States
- 4 Department of Internal Medicine-Pediatrics, Geisinger Medical Center, United States
Abstract
Cryptococcus neoformans is an encapsulated yeast that typically causes illness in immunocompromised hosts. Manifestations of the disease include pulmonary, Central Nervous System (CNS), and rare skeletal involvement. Optimal antifungal therapy for skeletal involvement has yet to be established. Here we present a potential antifungal regimen for disseminated cryptococcal disease with skeletal and pulmonary involvement in a patient with Chronic Lymphocytic Leukemia (CLL) on ibrutinib therapy.
DOI: https://doi.org/10.3844/ajidsp.2022.46.48
Copyright: © 2022 Nikko Rowe Asuncion Tabliago, Paula McKenzie, Caroline Dillon and Amelia Morgan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Cryptococcosis
- Osteomyelitis
- Fluconazole
- Disseminated