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Frequency: Quarterly
ISSN: 1553-6203 (Print)
ISSN: 1558-6340 (Online)
Case Report Open Access

Relapsing Cutaneous Leishmaniasis in a Patient Treated with Humira

Erik Otte1, Mikael Christiansen1 and Eskild Petersen1
  • 1 Aarhus University Hospital, Denmark

Abstract

Leishmanias is an anthropozoonosis caused by the Leishmania protozoa. The manifestation of the disease varies depending on the type of Leishmania and the immunestatus of the patient. Tumor Necrosis Factor (TNF)-α antagonists were introduced in the late 1990s and have had a marked impact on rheumatic diseases. Tumor necrosis factor plays an important role in the immune systems defense against intracellular infections and the use of TNF-α antagonists is linked with an increased frequency of infections. We here present a case of cutaneous leishmaniasis relapse following treatment with miltefosine and amphotericin B, in a patient undergoing treatment with a TNF-α antagonist.

American Journal of Infectious Diseases
Volume 11 No. 1, 2015, 7-10

DOI: https://doi.org/10.3844/ajidsp.2015.7.10

Submitted On: 3 December 2014 Published On: 9 June 2015

How to Cite: Otte, E., Christiansen, M. & Petersen, E. (2015). Relapsing Cutaneous Leishmaniasis in a Patient Treated with Humira. American Journal of Infectious Diseases, 11(1), 7-10. https://doi.org/10.3844/ajidsp.2015.7.10

Open AccessCopyright: © 2015 Erik Otte, Mikael Christiansen and Eskild Petersen. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • Cutaneous Leishmaniasis
  • Humira
  • Adalimumab
  • TNF-α Antagonist
  • Amphotericin B